Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL1408904 | 0.88 | CA4 (0.42) | TSHR | |
| SCHEMBL27725186 | 0.88 | CA4 (0.42) | LMNATSHR | |
| SCHEMBL8561065 | 0.86 | LMNA (0.45) | LMNATSHRSLC22A6FOLH1TDP1 | |
| SCHEMBL2201756 | 0.85 | TSHR (0.43) | TSHRSLC22A6TDP1BLM | |
| SCHEMBL28316038 | 0.84 | LMNA (0.43) | LMNATSHRSLC22A6FOLH1TDP1 | |
| SCHEMBL29165564 | 0.80 | LMNA (0.39) | LMNATSHRSLC22A6FOLH1TDP1 | |
| Adipic Acid SCHEMBL28878629 | 0.80 | LMNA (0.48) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL18614732 | 0.80 | CAMK2A (0.37) | LMNATSHRSLC22A6GPR84FFAR1 | |
| SCHEMBL14918857 | 0.80 | GPR84 (0.44) | GPR84FFAR1FFAR4 | |
| SCHEMBL28135218 | 0.80 | NFKB1 (0.44) | LMNATSHRNFKB1PMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077871-A1 | SALTS OF TEGASEROD | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | claimed |
| EP-1939176-A1 | Salts of Tegaserod | Novartis AG (CH) | 2008-07-02 | — | — | EP | claimed |
| CN-113993826-B | Interlayer film for laminated glass, roll, and laminated glass | 积水化学工业株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-107208118-A | The non-natural microorganism of energy efficiency with raising | 基因组股份公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2008077871-A1 | SALTS OF TEGASEROD | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| EP-1939176-A1 | Salts of Tegaserod | Novartis AG (CH) | 2008-07-02 | — | — | EP | disclosed |