⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27584770 | 0.97 | — | — | |
| SCHEMBL84219 | 0.81 | — | — | |
| SCHEMBL9536247 | 0.81 | HMGCR (0.55) | — | |
| Hydrochloric Acid SCHEMBL1444247 | 0.79 | — | — | |
| SCHEMBL3312832 | 0.79 | — | — | |
| Citric Acid SCHEMBL238240 | 0.78 | ALDH1A1 (0.75) | — | |
| SCHEMBL1660876 | 0.77 | TSHR (0.55) | — | |
| SCHEMBL9421510 | 0.77 | — | — | |
| SCHEMBL4760957 | 0.77 | — | — | |
| SCHEMBL1875520 | 0.77 | TSHR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124593-A1 | BRANCHED PEPTIDE AMPLIFICATION AND USES THEREOF | UNIVERSITE LAVAL (CA) | 2007-11-08 | — | — | WO | claimed |
| US-4521408-A | Antibiotics-859A and production thereof | MERCK & CO., INC. (US) | 1985-06-04 | — | — | US | claimed |
| CN-109790202-B | Cyclic peptide, affinity chromatography carrier, labeled antibody, antibody drug complex and pharmaceutical preparation | 富士胶片株式会社 | 2022-09-13 | — | — | CN | disclosed |
| CN-107810008-B | PIRIN polypeptides and immunomodulation | 4D制药研究有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-108137651-B | Cyclic peptide, affinity chromatography carrier, labeled antibody, antibody drug complex and pharmaceutical preparation | 富士胶片株式会社 | 2022-02-22 | — | — | CN | disclosed |
| CN-111334299-B | Etching liquid and preparation method thereof | 成都中电熊猫显示科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-111183156-A | Compositions and methods for treating cancer with anti-CD 19/CD20 immunotherapy | 莱蒂恩技术公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-109790202-A | Cyclic peptide, affinity chromatography carrier, labeled antibody, antibody drug complex and pharmaceutical preparation | 富士胶片株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-108137651-A | Cyclic peptide, affinity chromatography carrier, labelled antibody, antibody drug compound and pharmaceutical preparation | 富士胶片株式会社 | 2018-06-08 | — | — | CN | disclosed |
| WO-2018068757-A1 | CYCLOHEPTAPEPTIDE AGENTS FOR TREATMENT OF CANCER AND OBESITY DISEASES | HONG KONG BAPTIST UNIVERSITY (CN) | 2018-04-19 | — | — | WO | disclosed |
| CN-107847583-A | Pegylated interleukin-10 for the treatment of cancer | 阿尔莫生物科技股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| US-5644016-A | Maleimide copolymer as alignment layer for liquid-crystal displays | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-01 | — | — | US | disclosed |
| US-5385932-A | Anticholesterol, antilipemic agents | MERCK & CO., INC. (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0415488-B1 | 7-Substituted HMG-COA reductase inhibitors | MERCK & CO INC (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5112857-A | Anticholesterol, antilipemic | MERCK & CO., INC. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0323867-B1 | NOVEL HMG-COA REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-5098931-A | Anticholesterol agents or antilipemic agents | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0474291-A1 | HMG-COA reductase inhibitor metabolites | MERCK & CO. INC. (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4857547-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | MERCK & CO., INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0323867-A1 | Novel HMG-COA reductase inhibitors | MERCK & CO. INC. (US) | 1989-07-12 | — | — | EP | disclosed |