⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288787 | 0.79 | — | — | |
| SCHEMBL84219 | 0.79 | — | — | |
| SCHEMBL9536247 | 0.79 | HMGCR (0.55) | — | |
| SCHEMBL22561574 | 0.78 | HMGCR (0.48) | — | |
| SCHEMBL7252624 | 0.78 | HMGCR (0.61) | — | |
| Hydrochloric Acid SCHEMBL1444247 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27584770 | 0.77 | — | — | |
| SCHEMBL28122018 | 0.77 | — | — | |
| Citric Acid SCHEMBL238240 | 0.76 | ALDH1A1 (0.75) | — | |
| SCHEMBL11898737 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729006-A | Cyclic peptide compounds having Kras inhibitory activity | 中外制药株式会社 | 2022-07-08 | — | — | CN | claimed |
| EP-2413972-B1 | BONDING PRODUCTS OF AMINATED POLYSACCHARIDES | BRAUN MELSUNGEN AG (DE) | 2021-03-10 | — | — | EP | claimed |
| CN-110799520-B | Method for synthesizing peptides containing N-substituted amino acids | 中外制药株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-115716922-A | Lignin demethylation method based on low-cost proton type ionic liquid | 北京理工大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114729006-A | Cyclic peptide compounds having Kras inhibitory activity | 中外制药株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-114053835-A | Composite potassium carbonate absorbent for removing carbon dioxide and application thereof | 西南化工研究设计院有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-110869544-A | Cyclic peptide compound having high membrane permeability and library containing same | 中外制药株式会社 | 2020-03-06 | — | — | CN | disclosed |
| CN-110799520-A | Method for synthesizing peptides containing N-substituted amino acids | 中外制药株式会社 | 2020-02-14 | — | — | CN | disclosed |
| CN-103502248-A | Pyrazolo pyrimidine derivatives | NOVARTIS AG | 2014-01-08 | — | — | CN | disclosed |
| EP-0485525-B1 | MONOCLONAL ANTIBODY TO ACETYLATED LYSINE RESIDUES IN RECOMBINANT BOVINE SOMATOTROPIN | UPJOHN CO (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0559769-A4 | HEPARIN BINDING MITOGEN WITH HOMOLOGY TO EPIDERMAL GROWTH FACTOR (EGF) | CHILDRENS MEDICAL CENTER (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0559769-A1 | HEPARIN BINDING MITOGEN WITH HOMOLOGY TO EPIDERMAL GROWTH FACTOR (EGF) | The Children's Medical Center Corporation (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0485525-A1 | MONOCLONAL ANTIBODY TO ACETYLATED LYSINE RESIDUES IN RECOMBINANT BOVINE SOMATOTROPIN. | UPJOHN CO (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1992006705-A1 | HEPARIN BINDING MITOGEN WITH HOMOLOGY TO EPIDERMAL GROWTH FACTOR (EGF) | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1992-04-30 | — | — | WO | disclosed |
| EP-0446361-A1 | POLYPEPTIDE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION AND COSMETIC CONTAINING SAID POLYPEPTIDE | EARTH CHEMICAL CO., LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| WO-1991002080-A2 | MONOCLONAL ANTIBODY TO ACETYLATED LYSINE RESIDUES IN RECOMBINANT BOVINE SOMATOTROPIN | THE UPJOHN COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |
| US-4738904-A | CONTINUOUS REGENERATION | HUGHES AIRCRAFT COMPANY (US) | 1988-04-19 | — | — | US | disclosed |
| US-4247597-A | Electroscopic carrier particles having a carboxylic acid surface treatment | PITNEY BOWES, INC. (US) | 1981-01-27 | — | — | US | disclosed |