Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775536 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL1886237 | 0.96 | — | — | |
| SCHEMBL601895 | 0.89 | — | — | |
| SCHEMBL28087155 | 0.73 | — | — | |
| SCHEMBL3656726 | 0.73 | — | — | |
| SCHEMBL5281396 | 0.73 | — | — | |
| SCHEMBL8356448 | 0.73 | — | — | |
| SCHEMBL8507378 | 0.69 | — | — | |
| SCHEMBL1171187 | 0.69 | NR1H2 (0.32) | — | |
| SCHEMBL10465209 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | claimed |
| EP-4385979-A1 | MULTICYCLIC INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4385984-A1 | PYRIDINE-N-OXIDES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| WO-2024092185-A1 | ACYL SULFONAMIDE COMPOUNDS AS INHIBITORS OF POLYOMAVIRUS | VIA NOVA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| US-20240002395-A1 | COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN | THE JOHNS HOPKINS UNIVERSITY | 2024-01-04 | — | — | US | claimed |
| EP-4255893-A1 | COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN | The Johns Hopkins University (US) | 2023-10-11 | — | — | EP | claimed |
| EP-4196480-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2023-06-21 | — | — | EP | claimed |
| EP-4021441-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | Trustees of Dartmouth College (US) | 2022-07-06 | — | — | EP | claimed |
| WO-2022119823-A1 | COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-06-09 | — | — | WO | claimed |
| WO-2000018723-A1 | SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| CN-1193961-A | Substituted benzylaminopiperidine compounds | PFIZER (US) | 1998-09-23 | — | — | CN | claimed |
| EP-0861235-A1 | SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS | PFIZER INC. (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997008144-A1 | SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS | PFIZER PHARMACEUTICALS INC. (JP) | 1997-03-06 | — | — | WO | claimed |
| US-4687507-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-08-18 | — | — | US | claimed |
| US-4627873-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-09 | — | — | US | claimed |
| EP-0030138-B1 | HERBICIDAL SULFONAMIDES, AND COMPOSITIONS, PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-13 | — | — | EP | claimed |
| EP-0007687-B1 | SULFONAMIDES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SAID SULFONAMIDES AND A METHOD FOR CONTROLLING THE GROWTH OF VEGETATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-30 | — | — | EP | claimed |
| EP-0030138-A1 | Herbicidal sulfonamides, and compositions, preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | claimed |
| EP-0007687-A1 | Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-02-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002395-A1 | COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN | MRGPRX1, MRGPRX4, MRGPRX2 | ALDH1A1 4126/4885TRIM24 1767/4885TRIM33 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.