SCHEMBL28879158

SCHEMBL28879158

OB(O)O/C=C/c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
CES2 O00748 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
RPS6KA3 P51812 1/20 0.35
JAK3 P52333 1/20 0.35
IDO1 P14902 3/20 0.33
AHR P35869 1/20 0.33
TDO2 P48775 1/20 0.33
NQO2 P16083 1/20 0.33
MGLL Q99685 2/20 0.32
ORAI1 Q96D31 1/20 0.31
ORAI2 Q96SN7 1/20 0.31
ORAI3 Q9BRQ5 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879159 1.00 PTGS1 (0.41) PTGS1CES2CA1CA2RPS6KA3
SCHEMBL29429194 0.83 NFE2L2 (0.51) MGLL
SCHEMBL28799717 0.81 CA1 (0.54) PTGS1CA1CA2AHRNQO2
SCHEMBL28879179 0.81 CA1 (0.54) PTGS1CA1CA2AHRNQO2
SCHEMBL2909442 0.75 CA1 (0.59) PTGS1CES2CA1CA2RPS6KA3
SCHEMBL2909444 0.75 CA1 (0.59) PTGS1CES2CA1CA2RPS6KA3
SCHEMBL26070078 0.72 PTGS1 (0.66) PTGS1CA1CA2AHRNQO2
SCHEMBL466921 0.70 CES2 (0.41) CES2RPS6KA3JAK3IDO1TDO2
SCHEMBL13790220 0.69 PTGS1 (0.61) PTGS1CA1CA2IDO1AHR
SCHEMBL23633171 0.68 CES2 (0.40) CES2RPS6KA3JAK3IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138596-B Polymer electrolyte and lithium ion battery comprising same 珠海冠宇电池股份有限公司 2022-09-30 CN claimed