Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | BCR | P11274 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685934 | 0.83 | TAAR1 (0.55) | ADORA2AADORA1KDM4EMAPTMEN1 | |
| SCHEMBL12715050 | 0.81 | ABL1 (0.79) | ABL1ABCB1BCRMAPTLMNA | |
| SCHEMBL28970805 | 0.80 | ADORA2A (0.48) | ABL1ABCB1BCRADORA2AADORA1 | |
| SCHEMBL28879160 | 0.80 | KDM4E (0.49) | ADORA2AADORA1KDM4EMAPTMEN1 | |
| SCHEMBL29755699 | 0.79 | KDM4E (0.51) | ADORA2AADORA1KDM4EMAPTMEN1 | |
| SCHEMBL7116127 | 0.79 | KDM4E (0.51) | ADORA2AADORA1KDM4EMAPTMEN1 | |
| SCHEMBL11096260 | 0.79 | ABL1 (0.76) | ABL1ABCB1BCRMAPTLMNA | |
| SCHEMBL11819228 | 0.77 | ABL1 (0.73) | ABL1ABCB1BCRKDM4EMAPT | |
| SCHEMBL29007097 | 0.77 | MAPT (0.53) | ADORA2AADORA1KDM4EMAPTMEN1 | |
| SCHEMBL29213005 | 0.76 | PIN1 (0.45) | ABL1ABCB1BCRADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939903-B | Method for preparing furan compounds from bromoaryl ketone | 重庆医科大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-110143935-B | Preparation method of 2, 5-disubstituted furan derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |