Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22696464 | 0.83 | GRIN2D (0.41) | HTTPOLBNCOA1NCOA3GRIN2D | |
| SCHEMBL31569520 | 0.79 | MAPT (0.45) | HTTMAPTRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL5446122 | 0.79 | MAPT (0.45) | HTTMAPTRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL12355634 | 0.79 | ALDH1A1 (0.50) | HTTMAPTRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL18462460 | 0.79 | ALDH1A1 (0.47) | HTTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28307341 | 0.78 | HTT (0.45) | HTTPOLBNCOA1NCOA3GRIN2D | |
| SCHEMBL28332979 | 0.78 | HTT (0.41) | HTTPOLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28332985 | 0.78 | HTT (0.41) | HTTPOLBNCOA1NCOA3GRIN2D | |
| SCHEMBL25408774 | 0.75 | MAPT (0.43) | HTTPOLBMAPTTDP1MEN1 | |
| SCHEMBL28511817 | 0.75 | ALDH1A1 (0.38) | HTTMAPTRAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294751-A | Have the imidazoles [4,5-b] of bioactivity and pyridine compounds and their and its preparation method and application | 湖南化工研究院有限公司 | 2019-10-01 | — | — | CN | disclosed |