Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGMT | P16455 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307335 | 0.90 | HTT (0.38) | HTTPOLBNPY1RMAPTGAA | |
| SCHEMBL28307334 | 0.87 | TLR8 (0.37) | HTTPOLBNPY1RMAPTGAA | |
| SCHEMBL28306175 | 0.81 | MAPT (0.43) | HTTPOLBMAPTTDP1MGMT | |
| SCHEMBL28307339 | 0.81 | MAPT (0.38) | HTTMAPTGAATDP1LMNA | |
| SCHEMBL28879241 | 0.78 | HTT (0.43) | HTTPOLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28307340 | 0.77 | MAPT (0.39) | HTTPOLBNPY1RMAPTTDP1 | |
| SCHEMBL28306191 | 0.76 | MAPT (0.33) | HTTPOLBMAPTTDP1MGMT | |
| SCHEMBL28332985 | 0.75 | HTT (0.41) | HTTPOLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28332979 | 0.75 | HTT (0.41) | HTTPOLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28306205 | 0.75 | KMT2A (0.35) | HTTMAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |