Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.54 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023830 | 0.86 | AKT1 (0.65) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL4385499 | 0.86 | AKT1 (0.65) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL19209055 | 0.79 | RECQL (0.55) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL19209057 | 0.79 | RECQL (0.55) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL14431152 | 0.77 | RECQL (0.53) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL29257489 | 0.76 | GPR52 (0.66) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL21296681 | 0.76 | GPR52 (0.66) | AKT1GPR52RECQLMAPTLMNA | |
| SCHEMBL21528207 | 0.75 | LMNA (0.47) | AKT1MAPTLMNARAB9ANPC1 | |
| SCHEMBL21528208 | 0.75 | LMNA (0.47) | AKT1MAPTLMNARAB9ANPC1 | |
| Benzoic Acid SCHEMBL28839137 | 0.75 | TSHR (0.48) | MAPTLMNAKMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483265-A | A kind of synthetic method of two olefine aldehydr or diene ketone compounds | UNIV NORTHWESTERN | 2019-11-22 | — | — | CN | disclosed |