SCHEMBL28879340

SCHEMBL28879340

COc1cc(OC)c(OC)c2c1CC(=O)C(c1ccccc1)O2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.42
ABCB1 P08183 1/20 0.42
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
PABPC1 P11940 1/20 0.41
APEX1 P27695 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
EIF4H Q15056 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 6/20 0.39
CYP19A1 P11511 3/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 3/20 0.38
SIRT1 Q96EB6 1/20 0.38
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28513252 0.89 CYP19A1 (0.46) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL28840935 0.89 CYP19A1 (0.46) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL29270987 0.86 CDK1 (0.44) GAAMAPTCYP3A4MAPK1LMNA
SCHEMBL10425234 0.82 KDM4E (0.46) ABCG2ABCB1KDM4EALDH1A1HPGD
SCHEMBL665266 0.81 CYP19A1 (0.51) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL17503283 0.81 NPC1 (0.45) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL6700109 0.81 CYP1A2 (0.38) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL29204371 0.80 CYP19A1 (0.42) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL17907271 0.79 KMT2A (0.44) ABCG2ABCB1GAAMAPTMEN1
SCHEMBL17907267 0.78 KMT2A (0.50) ABCG2ABCB1GAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110604774-A Traditional Chinese medicine composition for treating animal enteritis diarrhea and preparation method thereof 临沂金翠兽药有限公司 2019-12-24 CN disclosed
CN-110604762-A Traditional Chinese medicine composition for treating kidney-type infectious bronchitis of poultry and preparation method thereof 临沂金翠兽药有限公司 2019-12-24 CN disclosed