SCHEMBL17907267

SCHEMBL17907267

COc1cc(O)c2c(c1O)OC(c1ccccc1)C(=O)C2

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
PABPC1 P11940 1/20 0.50
APEX1 P27695 1/20 0.50
RECQL P46063 1/20 0.50
EIF4H Q15056 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP19A1 P11511 3/20 0.46
SIRT1 Q96EB6 7/20 0.44
ABCG2 Q9UNQ0 3/20 0.41
ABCB1 P08183 2/20 0.41
SIRT2 Q8IXJ6 2/20 0.40
SIRT5 Q9NXA8 2/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840935 0.89 CYP19A1 (0.46) KMT2AMEN1POLBGAAMAPT
SCHEMBL27715514 0.84 POLB (0.41) KMT2AMEN1POLBGAAMAPT
SCHEMBL28513252 0.84 CYP19A1 (0.46) KMT2AMEN1POLBGAAMAPT
SCHEMBL665266 0.84 CYP19A1 (0.51) KMT2AMEN1POLBGAAMAPT
SCHEMBL17503283 0.84 NPC1 (0.45) KMT2AMEN1POLBGAAMAPT
SCHEMBL28823060 0.81 MAPT (0.43) KMT2AMEN1POLBGAAMAPT
SCHEMBL28879340 0.78 ABCG2 (0.42) KMT2AMEN1POLBGAAMAPT
SCHEMBL29204371 0.78 CYP19A1 (0.42) KMT2AMEN1POLBGAAMAPT
SCHEMBL15573731 0.77 ABCG2 (0.56) KMT2AMEN1POLBGAAMAPT
SCHEMBL17907271 0.77 KMT2A (0.44) KMT2AMEN1POLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042897-B1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY AGENT, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING THE COMPOUND AMINO UP CO LTD (JP) 2019-09-11 EP disclosed
US-9573920-B2 Compound, medicine, anti-inflammatory, cosmetic, food and drink, and method for producing compound AMINO UP CHEMICAL CO., LTD (JP) 2017-02-21 US disclosed
US-20160207901-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND Amino Up Co., Ltd. (JP) 2016-07-21 US disclosed
EP-3042897-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND Amino Up Chemical Co., Ltd. (JP) 2016-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160207901-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND MPO, TNF, CUTA KMT2A 3025/4885MEN1 201/4885POLB 2261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.