Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18518062 | 0.87 | CRHBP (0.52) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL16581288 | 0.80 | CRHBP (0.46) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL31333141 | 0.79 | CRHBP (0.54) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29662848 | 0.79 | APEX1 (0.67) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL22717286 | 0.77 | CRHBP (0.62) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL1231019 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL31197565 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29823876 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL24442811 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL30503055 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957310-A | Trisilyl polycarboxylic organic silicon compound and synthesis method and application thereof | 同济大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114957310-A | Trisilyl polycarboxylic organic silicon compound and synthesis method and application thereof | 同济大学 | 2022-08-30 | — | — | CN | disclosed |