Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823876 | 1.00 | CRHBP (0.50) | CRHBPCRHR2ALDH1A1MAPK1ALOX5 | |
| SCHEMBL31197565 | 1.00 | CRHBP (0.50) | CRHBPCRHR2ALDH1A1MAPK1ALOX5 | |
| SCHEMBL25501487 | 0.96 | CRHBP (0.47) | CRHBPCRHR2ALDH1A1MAPK1ALOX5 | |
| SCHEMBL16107210 | 0.82 | L3MBTL1 (0.48) | CRHBPCRHR2ALDH1A1MAPK1MEN1 | |
| SCHEMBL14883138 | 0.82 | ALDH1A1 (0.48) | CRHBPCRHR2ALDH1A1MAPK1ALOX5 | |
| SCHEMBL29690184 | 0.81 | ESR1 (0.48) | ALDH1A1ALOX5ESR2MEN1MAPT | |
| SCHEMBL27105052 | 0.81 | ESR1 (0.48) | ALDH1A1ALOX5ESR2MEN1MAPT | |
| SCHEMBL22548367 | 0.81 | ALDH1A1 (0.39) | CRHBPCRHR2ALDH1A1MAPK1ALOX5 | |
| SCHEMBL16107140 | 0.79 | MEN1 (0.51) | ALDH1A1MAPK1MAOAMEN1MAPT | |
| SCHEMBL27105065 | 0.78 | CRHBP (0.47) | CRHBPCRHR2ALDH1A1MAPK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213444-A | Tetraphenylsilane derivative and preparation method thereof | 陕西维世诺新材料有限公司 | 2022-03-22 | — | — | CN | claimed |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20250176429-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2025-05-29 | — | — | US | disclosed |
| US-20250115574-A1 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | VIB VZW (BE) | 2025-04-10 | — | — | US | disclosed |
| EP-4452253-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| CN-111072661-B | Organic electroluminescent device and amine compound for organic electroluminescent device | 三星显示有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-11937499-B2 | Aromatic amine derivative and organic electroluminescent devices containing the same | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2024-03-19 | — | — | US | disclosed |
| US-20110024731-A1 | NOVEL CONDENSED POLYCYCLIC AROMATIC COMPOUND AND USE THEREOF | NATIONAL UNIVERSITY OF CORP. HIROSHIMA UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
| US-7834198-B2 | Condensed polycyclic aromatic compound and use thereof | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7834198-B2 | Condensed polycyclic aromatic compound and use thereof | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7834198-B2 | Condensed polycyclic aromatic compound and use thereof | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2010-11-16 | — | — | US | disclosed |
| CN-101103037-B | Novel condensed polycyclic aromatic compound and use thereof | NAT UNIVERSITY OF CORP HIROSHI | 2010-10-13 | — | — | CN | disclosed |
| US-20090001357-A1 | Novel Condensed Polycyclic Aromatic Compound and Use Thereof | NATIONAL UNIVERSITY OF CORP. HIROSHIMA UNIVERSITY (JP) | 2009-01-01 | — | — | US | disclosed |
| US-20090001357-A1 | Novel Condensed Polycyclic Aromatic Compound and Use Thereof | NATIONAL UNIVERSITY OF CORP. HIROSHIMA UNIVERSITY (JP) | 2009-01-01 | — | — | US | disclosed |
| US-20090001357-A1 | Novel Condensed Polycyclic Aromatic Compound and Use Thereof | NATIONAL UNIVERSITY OF CORP. HIROSHIMA UNIVERSITY (JP) | 2009-01-01 | — | — | US | disclosed |
| CN-101103037-A | Novel condensed polycyclic aromatic compound and use thereof | NAT UNIVERSITY OF CORP HIROSHI (JP) | 2008-01-09 | — | — | CN | disclosed |
| EP-1847544-A1 | NOVEL CONDENSED POLYCYCLIC AROMATIC COMPOUND AND USE THEREOF | National University of Corporation Hiroshima University (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110024731-A1 | NOVEL CONDENSED POLYCYCLIC AROMATIC COMPOUND AND USE THEREOF | HCN4, HCN2, CTCF | CRHBP 3747/4885CRHR2 1754/4885ALDH1A1 4045/4885 |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | CRHBP 3864/4885CRHR2 3996/4885ALDH1A1 1935/4885 |
| US-11937499-B2 | Aromatic amine derivative and organic electroluminescent devices containing the same | TYR, DDC, AOC2 | CRHBP 4496/4885CRHR2 4523/4885ALDH1A1 232/4885 |
| US-20090001357-A1 | Novel Condensed Polycyclic Aromatic Compound and Use Thereof | HCN4, HCN2, CTCF | CRHBP 3747/4885CRHR2 1754/4885ALDH1A1 4045/4885 |
| US-12030866-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | CRHBP 3257/4885CRHR2 4282/4885ALDH1A1 2212/4885 |
| US-20250115574-A1 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | CRHBP 3257/4885CRHR2 4282/4885ALDH1A1 2212/4885 |
| US-20250176429-A1 | MATERIALS FOR ELECTRONIC DEVICES | ETV6, ERCC1, EED | CRHBP 3730/4885CRHR2 3554/4885ALDH1A1 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.