Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879714 | 0.91 | CYP1A2 (0.47) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL23409273 | 0.82 | KMT2A (0.50) | ALDH1A1CYP1A2MEN1KMT2ARAB9A | |
| SCHEMBL23111942 | 0.82 | KMT2A (0.50) | ALDH1A1CYP1A2MEN1KMT2ARAB9A | |
| SCHEMBL7981605 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL29602251 | 0.73 | KMT2A (0.50) | ALDH1A1CYP1A2MEN1KMT2ARAB9A | |
| SCHEMBL23111943 | 0.73 | KMT2A (0.50) | ALDH1A1CYP1A2MEN1KMT2ARAB9A | |
| SCHEMBL28879715 | 0.71 | HTR2A (0.47) | ALDH1A1CYP1A2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL342477 | 0.70 | LMNA (0.44) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL8067996 | 0.70 | ALDH1A1 (0.59) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL32681314 | 0.70 | CYP1A2 (0.54) | ALDH1A1CYP1A2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314659-B | synthesis and application of epsilon- (1-o-nitrophenyl) ethoxycarbonyl-L-lysine-N-carboxylic anhydride | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2019-12-10 | — | — | CN | claimed |
| CN-108314659-B | synthesis and application of epsilon- (1-o-nitrophenyl) ethoxycarbonyl-L-lysine-N-carboxylic anhydride | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2019-12-10 | — | — | CN | disclosed |