SCHEMBL28879953

SCHEMBL28879953

NCc1ccc(SCl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.50
LOXL2 Q9Y4K0 7/20 0.48
ABAT P80404 1/20 0.46
TAAR1 Q96RJ0 2/20 0.42
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
F10 P00742 1/20 0.39
F11 P03951 1/20 0.39
PNMT P11086 1/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
MAPT P10636 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25435922 0.78 HRH3 (0.55) HRH3LOXL2ABATTAAR1CA1
SCHEMBL15828 0.76 HRH3 (0.79) HRH3LOXL2ABATTAAR1CA1
SCHEMBL11250295 0.76 NR1H2 (0.32) MAPT
SCHEMBL7643258 0.76 HRH3 (0.52) HRH3LOXL2ABATTAAR1CA1
SCHEMBL18410918 0.74 LOXL2 (0.52) HRH3LOXL2ABATTAAR1CA1
SCHEMBL9303786 0.74 TRPA1 (0.43)
SCHEMBL2018103 0.74 TP53 (0.43) TAAR1CA2
SCHEMBL23891959 0.74 ABAT (0.52) HRH3LOXL2ABATTAAR1CA1
SCHEMBL2092148 0.74 SLC6A4 (0.61) HRH3LOXL2ABAT
SCHEMBL5790074 0.73 MAOB (0.52) HRH3LOXL2TAAR1PNMTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed