Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.70 |
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | BACE1 | P56817 | 4/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.70 |
| ▸ | MMP9 | P14780 | 3/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | STAT3 | P40763 | 2/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986453 | 1.00 | APP (0.70) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL29985498 | 0.92 | ALOX5 (0.74) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL28880283 | 0.88 | ALOX5 (0.70) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL28880317 | 0.87 | ALOX5 (0.72) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL29985856 | 0.87 | ALOX5 (0.72) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL14586438 | 0.87 | APP (0.89) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL31206242 | 0.87 | APP (0.89) | APPMAPTBACE1NFKB1MMP9 | |
| SCHEMBL13580581 | 0.84 | APP (0.80) | APPMAPTBACE1NFKB1MMP9 | |
| Curcumin SCHEMBL28005444 | 0.84 | APP (0.94) | APPMAPTBACE1NFKB1MMP9 | |
| Curcumin SCHEMBL26626638 | 0.84 | APP (0.94) | APPMAPTBACE1NFKB1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229056-B | Novel curcumin analogue and preparation method and application thereof | 天津科技大学 | 2022-11-08 | — | — | CN | disclosed |