Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.70 |
| ▸ | PTGES | O14684 | 3/20 | 0.59 |
| ▸ | STAT3 | P40763 | 3/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985498 | 0.96 | ALOX5 (0.74) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL28880317 | 0.91 | ALOX5 (0.72) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL29985856 | 0.91 | ALOX5 (0.72) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL28880249 | 0.88 | APP (0.70) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL29986453 | 0.88 | APP (0.70) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL29986042 | 0.86 | ALOX5 (0.65) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL28880315 | 0.86 | ALOX5 (0.65) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL4840703 | 0.86 | PKM (0.68) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL4840709 | 0.86 | PKM (0.68) | ALOX5PTGESSTAT3NFE2L2PTGS1 | |
| SCHEMBL14253555 | 0.81 | ALOX5 (0.60) | ALOX5PTGESSTAT3NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229056-B | Novel curcumin analogue and preparation method and application thereof | 天津科技大学 | 2022-11-08 | — | — | CN | disclosed |