Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 13/20 | 0.54 |
| ▸ | PREP | P48147 | 12/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880394 | 1.00 | FAP (0.54) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28880424 | 0.87 | PREP (0.54) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28880426 | 0.87 | PREP (0.54) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28880404 | 0.84 | PREP (0.52) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28880405 | 0.84 | PREP (0.52) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL29911417 | 0.83 | FAP (0.53) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28880390 | 0.83 | FAP (0.53) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28880389 | 0.83 | FAP (0.53) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28958451 | 0.83 | FAP (0.55) | FAPPREPDPP9PITRM1DPP8 | |
| SCHEMBL28958456 | 0.83 | FAP (0.55) | FAPPREPDPP9PITRM1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160204-B | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2024-04-09 | — | — | CN | claimed |
| CN-115160204-A | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160204-B | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115160204-A | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2022-10-11 | — | — | CN | disclosed |