Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 17/20 | 0.52 |
| ▸ | FAP | Q12884 | 14/20 | 0.52 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880405 | 1.00 | PREP (0.52) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880452 | 0.90 | PREP (0.52) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28958451 | 0.90 | FAP (0.55) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880453 | 0.90 | PREP (0.52) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28958456 | 0.90 | FAP (0.55) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880424 | 0.89 | PREP (0.54) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880426 | 0.89 | PREP (0.54) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880392 | 0.84 | FAP (0.54) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880394 | 0.84 | FAP (0.54) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL28880390 | 0.81 | FAP (0.53) | PREPFAPDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160204-B | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2024-04-09 | — | — | CN | claimed |
| CN-115160204-A | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160204-B | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115160204-A | Fibroblast activation protein inhibitor and preparation method and application thereof | 山东大学 | 2022-10-11 | — | — | CN | disclosed |