SCHEMBL28880448

SCHEMBL28880448

CC(=O)OCC(CNC(=O)c1c(I)c(N)c(I)c(C(N)=O)c1I)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
ABCB1 P08183 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1359798 0.96 LMNA (0.38) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL9515975 0.94 ABCB1 (0.37) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL8063052 0.92 LMNA (0.36) LMNACYP2C19HIF1AABCB1TDP1
Hydrochloric Acid SCHEMBL8857263 0.91 LMNA (0.35) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL9009046 0.91 LMNA (0.35) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL8374103 0.90 LMNA (0.34) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL8377049 0.89 LMNA (0.36) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL7986029 0.88 LMNA (0.35) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL8374414 0.88 LMNA (0.34) LMNACYP2C19HIF1AABCB1TDP1
SCHEMBL8905997 0.87 LMNA (0.38) LMNACYP2C19HIF1AABCB1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160174-A Synthesis method of ioversol 浙江海洲制药有限公司 2022-10-11 CN claimed
CN-115160174-A Synthesis method of ioversol 浙江海洲制药有限公司 2022-10-11 CN disclosed
CN-115160174-A Synthesis method of ioversol 浙江海洲制药有限公司 2022-10-11 CN disclosed