Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17124727 | 0.95 | LMNA (0.41) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL9009279 | 0.91 | LMNA (0.49) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL8377994 | 0.91 | LMNA (0.38) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL28880451 | 0.90 | LMNA (0.43) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL9009328 | 0.90 | LMNA (0.38) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL4927394 | 0.90 | LMNA (0.38) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL9563072 | 0.89 | LMNA (0.37) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL8379840 | 0.88 | LMNA (0.39) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL8741511 | 0.87 | LMNA (0.39) | LMNACYP2C19HIF1ASMN1; SMN2ABCB1 | |
| SCHEMBL28880448 | 0.87 | LMNA (0.36) | LMNACYP2C19HIF1AABCB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816868-B | Synthesis method of iohexol | 浙江海洲制药有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116253660-A | Synthesis method of iohexol | 辽宁药联制药有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113816868-A | Synthesis method of iohexol | 浙江海洲制药有限公司 | 2021-12-21 | — | — | CN | disclosed |
| US-5698739-A | RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |