SCHEMBL28880673

SCHEMBL28880673

CCCCC/C=C(/C=C/C(=O)OCCCC)CCC(=O)N(C)C

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
HCAR2 Q8TDS4 4/20 0.48
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
APP P05067 5/20 0.35
FAAH O00519 2/20 0.34
EP300 Q09472 1/20 0.33
CNR1 P21554 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28342878 0.88 ATM (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28342912 0.82 ALDH1A1 (0.46) ATMHCAR2MAPTNPSR1ALDH1A1
SCHEMBL28340304 0.79 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28342900 0.78 L3MBTL1 (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28342852 0.74 ATM (0.53) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11684339 0.73 ATM (0.91) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11684344 0.73 ATM (0.91) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28153 0.72 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28154 0.72 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL269917 0.72 ATM (1.00) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642737-B Preparation method of amide-substituted (E, E) -configuration branched conjugated diene derivative 杭州师范大学 2022-08-05 CN disclosed
CN-110642737-A Amide-substituted (E, E) -configuration branched conjugated diene derivative and preparation method thereof 杭州师范大学 2020-01-03 CN disclosed