⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728592 | 0.78 | CA2 (0.41) | — | |
| SCHEMBL27253156 | 0.73 | CA2 (0.47) | — | |
| SCHEMBL208791 | 0.71 | — | — | |
| SCHEMBL695182 | 0.71 | — | — | |
| SCHEMBL3578716 | 0.71 | — | — | |
| SCHEMBL20446653 | 0.71 | — | — | |
| SCHEMBL9705409 | 0.69 | — | — | |
| SCHEMBL5841745 | 0.69 | — | — | |
| SCHEMBL20938248 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7623742 | 0.69 | CA2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118369325-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118355020-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-1546113-B1 | PYRIMIDINONE DERIVATIVES AS THERAPEUTIC AGENTS AGAINST ACUTE AND CHRONIC INFLAMMATORY, ISCHAEMIC AND REMODELLING PROCESSES | BAYER IP GMBH (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-7687510-B2 | Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes | BAYER HEALTHCARE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20060160801-A1 | Pyrimidinone derivaties as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-20 | — | — | US | disclosed |
| US-4954628-A | HERBICIDES, PLANT GROWTH REGULATORS, PHARMACEUTICALS | NITROKAELEPEK (HU) | 1990-09-04 | — | — | US | disclosed |