Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 4/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338794 | 0.89 | MRGPRX4 (0.41) | PNLIPPDE7ANR1H4MAPTESRRA | |
| SCHEMBL27751081 | 0.85 | FFAR1 (0.39) | PNLIPNR1H4MEN1KMT2AFFAR1 | |
| SCHEMBL3813706 | 0.80 | MAPT (0.51) | NR1H4MAPTGAAPKMKMT2A | |
| SCHEMBL28844759 | 0.79 | PDE7A (0.51) | PNLIPPDE7AMAPTMEN1GAA | |
| SCHEMBL3485177 | 0.78 | ACACB (0.43) | PNLIPPDE7AESRRAKMT2A | |
| SCHEMBL3506314 | 0.78 | POLB (0.48) | PNLIPPOLBKMT2ATDP1 | |
| SCHEMBL28880742 | 0.78 | PNLIP (0.52) | PNLIPPDE7AMAPTNPSR1ESRRA | |
| SCHEMBL3505758 | 0.77 | EGFR (0.52) | MAPTNPSR1POLBMEN1KMT2A | |
| SCHEMBL2748866 | 0.75 | ESRRA (0.45) | PNLIPPDE7ANR1H4ESRRAFFAR1 | |
| SCHEMBL27470803 | 0.75 | ACHE (0.43) | NR1H4MAPTPOLBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-A | Benzazole compounds and preparation method thereof, pharmaceutical composition and purposes | INST MATERIA MEDICA CAMS | 2019-11-22 | — | — | CN | disclosed |