Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339795 | 0.87 | HPGD (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20492724 | 0.87 | HPGD (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21065688 | 0.87 | HPGD (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20841005 | 0.79 | HPGD (0.45) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21413548 | 0.78 | MEN1 (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21841726 | 0.77 | HPGD (0.52) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21063795 | 0.75 | MAPT (0.43) | LMNAKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL20841022 | 0.75 | HPGD (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24240531 | 0.75 | LMNA (0.43) | LMNAKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL6772037 | 0.73 | MEN1 (0.60) | KMT2AMEN1SMN1; SMN2DHFROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601822-A | Antibody construct-drug conjugates for the treatment of hepatitis | 希沃尔拜克治疗公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-110612104-A | Benzazepine compounds, conjugates and uses thereof | 希沃尔拜克治疗公司 | 2019-12-24 | — | — | CN | disclosed |