Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880958 | 0.87 | HPGD (0.53) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20492672 | 0.87 | MEN1 (0.48) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24240443 | 0.86 | MEN1 (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28342305 | 0.81 | TDP1 (0.42) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20841157 | 0.80 | HPGD (0.43) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20492781 | 0.80 | ALDH1A1 (0.43) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20492552 | 0.78 | DRD2 (0.42) | LMNAKMT2AMEN1POLBABCB1 | |
| SCHEMBL21063758 | 0.76 | ALDH1A1 (0.46) | LMNAKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL6766529 | 0.75 | RAB9A (0.54) | LMNAKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL21065688 | 0.74 | HPGD (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601822-A | Antibody construct-drug conjugates for the treatment of hepatitis | 希沃尔拜克治疗公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-110612104-A | Benzazepine compounds, conjugates and uses thereof | 希沃尔拜克治疗公司 | 2019-12-24 | — | — | CN | disclosed |