Dimethylformamide

Dimethylformamide

SCHEMBL28882249

CN(C)C=O.Cc1ccc([SH](=O)=O)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.39
TSHR P16473 2/20 0.39
LMNA P02545 3/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
ACHE P22303 1/20 0.35
MAP1LC3B Q9GZQ8 1/20 0.33
CHRNA7 P36544 1/20 0.32
MAPT P10636 2/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
ATM Q13315 3/20 0.31
PKM P14618 2/20 0.31
HTT P42858 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
NLRP1 Q9C000 1/20 0.31
TLR9 Q9NR96 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13743035 0.83 ACHE (0.50) CYP2A6LMNAGAAALDH1A1HPGD
P-Xylene SCHEMBL4351291 0.83 TSHR (0.56) CYP2A6TSHRLMNAGAAALDH1A1
SCHEMBL29152107 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
Hydrogen Sulfide SCHEMBL28088406 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
SCHEMBL27564735 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
Water SCHEMBL25409091 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
SCHEMBL27836143 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
SCHEMBL27756606 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
SCHEMBL28724358 0.81 ACHE (0.47) CYP2A6LMNAGAAALDH1A1HPGD
SCHEMBL340079 0.77 ACHE (0.42) CYP2A6LMNAGAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110430897-A Engage unit and the molecule construct comprising engaging unit IMMUNWORK INC 2019-11-08 CN disclosed