Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898228 | 0.76 | TDP1 (0.43) | MAPTPKMTDP1LMNAATM | |
| SCHEMBL27647542 | 0.75 | TDP1 (0.51) | SSTR4TDP1ATMMTNR1ACYP2D6 | |
| SCHEMBL20520342 | 0.72 | TDP1 (0.56) | SSTR4MAPTTDP1ATMGRM2 | |
| SCHEMBL29914128 | 0.72 | TDP1 (0.56) | SSTR4MAPTTDP1ATMGRM2 | |
| SCHEMBL28688898 | 0.71 | CDC25B (0.49) | MAPTTDP1LMNAKDM4EMEN1 | |
| SCHEMBL29207386 | 0.70 | ADRA2A (0.51) | MAPTLMNACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL29981949 | 0.70 | TDP1 (0.53) | SSTR4MAPTTDP1GRM2GRM3 | |
| SCHEMBL6531713 | 0.70 | TDP1 (0.53) | SSTR4MAPTTDP1GRM2GRM3 | |
| SCHEMBL7037475 | 0.69 | CYP1A2 (0.50) | SSTR4MAPTTDP1LMNAMTNR1A | |
| SCHEMBL28346039 | 0.68 | HPGD (0.45) | SSTR4TDP1LMNAMTNR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340468-A | (R) -deuterated phenylalanine derivative and preparation method thereof | 西南大学 | 2022-11-15 | — | — | CN | disclosed |