Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958684 | 0.86 | KDM4E (0.37) | PKMKDM4ENQO2TYMSCYP1A2 | |
| SCHEMBL28883427 | 0.82 | KDM4E (0.34) | KDM4ENQO2CYP1A2CYP2C19TNKS2 | |
| SCHEMBL28883403 | 0.79 | AR (0.34) | KDM4ENQO2CYP1A2CYP2C19TNKS2 | |
| SCHEMBL28883380 | 0.77 | MEN1 (0.34) | PKMKDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL28883360 | 0.75 | MEN1 (0.38) | CYP1A2CYP2C19KMT2AMEN1L3MBTL1 | |
| SCHEMBL29999851 | 0.73 | AR (0.34) | KDM4EALDH1A1TSHRMGLL | |
| SCHEMBL28883580 | 0.73 | AR (0.34) | KDM4EALDH1A1TSHRMGLL | |
| SCHEMBL28883319 | 0.73 | TSHR (0.46) | PKMCYP1A2KMT2AALDH1A1POLB | |
| SCHEMBL3681378 | 0.71 | DPP4 (0.33) | DPP4ANPEPKMT2AMEN1L3MBTL1 | |
| SCHEMBL26659407 | 0.71 | GAA (0.44) | PKMKDM4EDPP4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |