Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XPO1 | O14980 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883380 | 0.90 | MEN1 (0.34) | MEN1KMT2ANPSR1HPGDSMN1; SMN2 | |
| SCHEMBL28958684 | 0.78 | KDM4E (0.37) | MEN1KMT2AHPGDXPO1CYP1A2 | |
| SCHEMBL28883464 | 0.77 | MGLL (0.48) | MEN1KMT2ANPSR1HPGDSMN1; SMN2 | |
| SCHEMBL28883391 | 0.75 | PKM (0.39) | MEN1KMT2ASMN1; SMN2XPO1CYP1A2 | |
| SCHEMBL28883427 | 0.75 | KDM4E (0.34) | MEN1KMT2AXPO1CYP1A2CYP2C19 | |
| SCHEMBL20261815 | 0.72 | MGLL (0.56) | MEN1KMT2ASMN1; SMN2XPO1MAPT | |
| SCHEMBL8886696 | 0.72 | ALDH1A1 (0.38) | NPSR1HPGDXPO1MAPTCYP2C19 | |
| SCHEMBL28883362 | 0.70 | MGLL (0.44) | MEN1KMT2ANPSR1HPGDSMN1; SMN2 | |
| SCHEMBL28883454 | 0.70 | L3MBTL1 (0.43) | MEN1KMT2ANPSR1HPGDSMN1; SMN2 | |
| SCHEMBL28883474 | 0.70 | L3MBTL1 (0.40) | MEN1KMT2ANPSR1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |