Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883380 | 0.86 | MEN1 (0.34) | KDM4ECYP1A2XPO1MEN1KMT2A | |
| SCHEMBL28883391 | 0.86 | PKM (0.39) | KDM4ENQO2CYP1A2CYP2C19TNKS2 | |
| SCHEMBL28883427 | 0.86 | KDM4E (0.34) | KDM4ENQO2CYP1A2CYP2C19TNKS2 | |
| SCHEMBL28883403 | 0.83 | AR (0.34) | KDM4ENQO2CYP1A2CYP2C19TNKS2 | |
| SCHEMBL28883580 | 0.83 | AR (0.34) | KDM4EMGLLALDH1A1HPGD | |
| SCHEMBL29999851 | 0.83 | AR (0.34) | KDM4EMGLLALDH1A1HPGD | |
| SCHEMBL28883393 | 0.82 | TDP1 (0.40) | KDM4ECYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL28883387 | 0.80 | TSHR (0.34) | KDM4ENQO2MEN1KMT2AALDH1A1 | |
| SCHEMBL28883483 | 0.80 | MGLL (0.48) | KDM4ENQO2CYP1A2CYP2C19TNKS2 | |
| SCHEMBL28883319 | 0.79 | TSHR (0.46) | CYP1A2XPO1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |