Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 16/20 | 0.57 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884249 | 1.00 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL28884201 | 0.95 | ITGB1 (0.62) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455393 | 0.93 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL30001027 | 0.93 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455394 | 0.93 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL28884210 | 0.89 | ITGB1 (0.73) | ITGB1ITGA5ITGA4PRMT5WDR77 | |
| SCHEMBL23455519 | 0.87 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77HDAC3 | |
| SCHEMBL23455521 | 0.87 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77HDAC3 | |
| SCHEMBL30001345 | 0.87 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77HDAC3 | |
| SCHEMBL28884197 | 0.87 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348861-A | Alpha-5 beta-1 inhibitors | 加利福尼亚大学董事会 | 2022-11-15 | — | — | CN | disclosed |