SCHEMBL28884337

SCHEMBL28884337

CCCCC(CCCCCCO)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.35
CA2 P00918 2/20 0.35
PTPN1 P18031 1/20 0.32
PSMD14 O00487 1/20 0.32
PLA2G1B P04054 1/20 0.32
MMP2 P08253 1/20 0.32
RAD52 P43351 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
FDPS P14324 1/20 0.31
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27089875 0.97 LMNA (0.43) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8499855 0.97 LMNA (0.43) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL517801 0.93 LMNA (0.30) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1326475 0.92 SMN1; SMN2 (0.37) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL22391537 0.92 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL29108482 0.92 SMN1; SMN2 (0.32) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL12865774 0.92 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL22391538 0.92 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL19385898 0.90 LMNA (0.35) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL14834118 0.88 CA2 (0.36) LMNATSHRCA2FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079679-B Asymmetric total synthesis method of sex pheromone (R, Z) -21-methyl-8-thirty-five carbene of longicorn 塔里木大学 2022-10-11 CN claimed
CN-112079679-B Asymmetric total synthesis method of sex pheromone (R, Z) -21-methyl-8-thirty-five carbene of longicorn 塔里木大学 2022-10-11 CN disclosed