Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129049 | 0.84 | SMN1; SMN2 (0.46) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL22520234 | 0.81 | TDP1 (0.43) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL1822997 | 0.79 | PYCR1 (0.44) | TDP1ALOX15SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL5032198 | 0.76 | ALOX15 (0.56) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL30316721 | 0.76 | ALOX15 (0.56) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL4001757 | 0.76 | ALOX15 (0.56) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL29617187 | 0.76 | ALOX15 (0.56) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL5252467 | 0.76 | TDP1 (0.56) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL25275619 | 0.76 | CSNK2A1 (0.40) | TDP1ALOX15SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3920018 | 0.76 | PDE3B (0.41) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197135-B | Method for preparing polysubstituted quinoline compound by zinc catalysis | 鲁东大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-115197135-A | Method for preparing polysubstituted quinoline compound by zinc catalysis | 鲁东大学 | 2022-10-18 | — | — | CN | disclosed |