Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 4/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033317 | 0.95 | AKT1 (0.41) | SRPK1AKT1GAAHPGDSMN1; SMN2 | |
| SCHEMBL28378694 | 0.84 | CYP1A2 (0.53) | GAAHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL29033218 | 0.84 | CHEK1 (0.54) | IRAK4 | |
| SCHEMBL28378607 | 0.79 | CSF1R (0.51) | GAAHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL28382326 | 0.78 | PIM1 (0.40) | — | |
| SCHEMBL28887910 | 0.76 | PIM1 (0.41) | KDM4EMAPTIRAK4CYP1A2CYP2C9 | |
| SCHEMBL20598310 | 0.76 | CSF1R (0.55) | SRPK1GAAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL20598787 | 0.75 | SRPK1 (0.49) | SRPK1GAAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL20623024 | 0.75 | CSF1R (0.53) | SRPK1GAAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL20598149 | 0.75 | SRPK1 (0.58) | SRPK1GAAHPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-111032642-A | Kinase inhibitors and methods of making and using | 里格尔药品股份有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111032642-A | Kinase inhibitors and methods of making and using | 里格尔药品股份有限公司 | 2020-04-17 | — | — | CN | disclosed |