Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382359 | 0.95 | PIM1 (0.41) | PIM1PIM3BACE1ALDH1A1MAPT | |
| SCHEMBL28380087 | 0.89 | PIM1 (0.42) | PIM1PIM3BACE1ALDH1A1MAPT | |
| SCHEMBL28382326 | 0.88 | PIM1 (0.40) | PIM1PIM3 | |
| SCHEMBL28379245 | 0.83 | PIM1 (0.42) | PIM1PIM3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28378694 | 0.83 | CYP1A2 (0.53) | ALDH1A1MAPTL3MBTL1MAPK10NPSR1 | |
| SCHEMBL28383473 | 0.82 | PIM1 (0.39) | PIM1PIM3 | |
| SCHEMBL28383372 | 0.81 | IRAK4 (0.41) | PIM1PIM3BACE1MAPTIRAK4 | |
| SCHEMBL28382809 | 0.80 | PIM1 (0.43) | PIM1PIM3BACE1ALDH1A1MAPT | |
| SCHEMBL29033218 | 0.79 | CHEK1 (0.54) | IRAK4 | |
| SCHEMBL28378607 | 0.78 | CSF1R (0.51) | ALDH1A1MAPTL3MBTL1MAPK10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111032642-A | Kinase inhibitors and methods of making and using | 里格尔药品股份有限公司 | 2020-04-17 | — | — | CN | disclosed |