SCHEMBL28887348

SCHEMBL28887348

c1ccc2c(c1)ccc1c(Nc3cccc4c3[nH]c3ccccc34)cccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.62
TP53 P04637 2/20 0.44
MAPT P10636 2/20 0.44
BCHE P06276 1/20 0.44
JAK2 O60674 1/20 0.44
HTT P42858 1/20 0.44
KLK7 P49862 1/20 0.44
HPRT1 P00492 1/20 0.44
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRE P78334 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28887355 0.90 KIF11 (0.59) KIF11TP53MAPTBCHEJAK2
SCHEMBL28959019 0.85 KIF11 (0.54) KIF11TP53MAPTBCHEJAK2
SCHEMBL9490444 0.85 KIF11 (0.59) KIF11TP53MAPTJAK2HTT
SCHEMBL1275021 0.83 KIF11 (0.88) KIF11MAPTBCHEHPRT1GABRP
SCHEMBL10946899 0.83 KIF11 (0.88) KIF11MAPTBCHEHPRT1GABRP
SCHEMBL30963036 0.83 KIF11 (0.88) KIF11MAPTBCHEHPRT1GABRP
SCHEMBL9572742 0.83 HPRT1 (0.64) TP53MAPTHPRT1ALDH1A1CYP3A4
SCHEMBL6541282 0.83 HPRT1 (0.64) TP53MAPTHPRT1ALDH1A1CYP3A4
SCHEMBL29177985 0.83 KIF11 (0.46) KIF11BCHEPARP14CDC25BCDK4
SCHEMBL22189182 0.81 BCHE (0.55) KIF11TP53MAPTBCHEJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115336026-A Organic electroluminescent element 日铁化学材料株式会社 2022-11-11 CN disclosed