SCHEMBL28887355

SCHEMBL28887355

c1ccc2c(Nc3cccc4c3[nH]c3ccccc34)cccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.59
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 3/20 0.52
TP53 P04637 2/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 2/20 0.52
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.52
CDC25B P30305 1/20 0.52
ATM Q13315 1/20 0.52
MAPT P10636 2/20 0.49
BCHE P06276 1/20 0.49
JAK2 O60674 1/20 0.49
HTT P42858 1/20 0.49
KLK7 P49862 1/20 0.49
PARP14 Q460N5 7/20 0.47
GPR3 P46089 1/20 0.45
GABRP O00591 2/20 0.45
GABRD O14764 2/20 0.45
GABRA1 P14867 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9490444 0.91 KIF11 (0.59) KIF11ALDH1A1HSD17B10TP53CYP3A4
SCHEMBL28887348 0.90 KIF11 (0.62) KIF11ALDH1A1HSD17B10TP53CYP3A4
SCHEMBL22189182 0.87 BCHE (0.55) KIF11TP53MAPTBCHEJAK2
SCHEMBL28887325 0.87 KIF11 (0.49) KIF11ALDH1A1HSD17B10TP53CYP3A4
SCHEMBL28959019 0.84 KIF11 (0.54) KIF11ALDH1A1HSD17B10TP53CYP3A4
SCHEMBL22762732 0.83 KIF11 (0.49) KIF11BCHEPARP14
SCHEMBL49213 0.80 HSD17B10 (0.74) ALDH1A1HSD17B10TP53CYP3A4HPGD
SCHEMBL30346387 0.80 MAPT (0.59) KIF11ALDH1A1HSD17B10TP53CYP3A4
SCHEMBL8415803 0.80 MAPT (0.59) KIF11ALDH1A1HSD17B10TP53CYP3A4
SCHEMBL22189181 0.78 PARP14 (0.51) KIF11TP53CDC25BMAPTJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115336026-A Organic electroluminescent element 日铁化学材料株式会社 2022-11-11 CN disclosed