Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.80 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.80 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.80 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.80 |
| ▸ | PRKCA | P17252 | 13/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | GMNN | O75496 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | POLB | P06746 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | APEX1 | P27695 | 4/20 | 0.80 |
| ▸ | RECQL | P46063 | 4/20 | 0.80 |
| ▸ | BLM | P54132 | 4/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 3/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2331911 | 0.97 | PRKCA (0.83) | PRKCAMEN1KMT2AGMNNLMNA | |
| Laurolinium SCHEMBL29388527 | 0.93 | PRKCA (0.88) | PRKCAMEN1KMT2AGMNNLMNA | |
| SCHEMBL19490053 | 0.93 | PRKCA (0.88) | PRKCAMEN1KMT2AGMNNLMNA | |
| Hydrochloric Acid SCHEMBL9789749 | 0.91 | MEN1 (0.89) | PRKCAMEN1KMT2AGMNNLMNA | |
| Hydrochloric Acid SCHEMBL32681974 | 0.91 | MEN1 (0.89) | PRKCAMEN1KMT2AGMNNLMNA | |
| Iodide SCHEMBL2337776 | 0.91 | PRKCA (0.89) | PRKCAMEN1KMT2AGMNNLMNA | |
| Dequalinium SCHEMBL2993904 | 0.91 | PRKCA (0.97) | PRKCAMEN1KMT2AGMNNLMNA | |
| SCHEMBL6299633 | 0.89 | PRKCA (1.00) | PRKCAMEN1KMT2AGMNNLMNA | |
| Dequalinium SCHEMBL149457 | 0.89 | PRKCA (1.00) | PRKCAMEN1KMT2AGMNNLMNA | |
| SCHEMBL6298118 | 0.89 | PRKCA (1.00) | PRKCAMEN1KMT2AGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156679-B | Quinoline derivative fluorescent probe and preparation method and application thereof | 安徽大学 | 2022-10-21 | — | — | CN | disclosed |