Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | SNCA | P37840 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796498 | 1.00 | BCL2 (0.42) | BCL2PTGS1MEN1KMT2APTGS2 | |
| SCHEMBL29282180 | 0.83 | CYP19A1 (0.45) | PTGS1MEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL7809366 | 0.83 | CYP19A1 (0.45) | PTGS1MEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL677662 | 0.83 | TDP1 (0.57) | BCL2PTGS1MEN1KMT2APTGS2 | |
| SCHEMBL6822731 | 0.83 | TDP1 (0.57) | BCL2PTGS1MEN1KMT2APTGS2 | |
| SCHEMBL1508796 | 0.83 | MEN1 (0.49) | PTGS1MEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL349722 | 0.81 | CYP3A4 (0.52) | PTGS1MEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL3487578 | 0.81 | CYP3A4 (0.52) | PTGS1MEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL28616927 | 0.81 | RECQL (0.44) | PTGS1MEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL16151244 | 0.79 | KDM4E (0.54) | BCL2PTGS1MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110946935-A | Formula for treating multiple myeloma complicated with renal failure | 湖北妙威生物医药有限公司 | 2020-04-03 | — | — | CN | disclosed |