Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29282180 | 1.00 | CYP19A1 (0.45) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL1508796 | 0.89 | MEN1 (0.49) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL28616927 | 0.87 | RECQL (0.44) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL16151244 | 0.85 | KDM4E (0.54) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL8249167 | 0.85 | KDM4E (0.54) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL2781922 | 0.85 | KDM4E (0.54) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL3487578 | 0.85 | CYP3A4 (0.52) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL349722 | 0.85 | CYP3A4 (0.52) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL6822731 | 0.83 | TDP1 (0.57) | CYP19A1MEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL28888148 | 0.83 | BCL2 (0.42) | CYP19A1MEN1KMT2ACYP3A4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1096930-A1 | THERAPEUTIC COMPOSITION BASED ON FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS WITH CYTOTOXIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003706-A1 | THERAPEUTIC COMPOSITION BASED ON FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS WITH CYTOTOXIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |