SCHEMBL349722

SCHEMBL349722

O=C1Cc2c(O)cc(O)cc2OC1c1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
PTGS1 P23219 2/20 0.52
PTGS2 P35354 2/20 0.52
SYNJ2 O15056 1/20 0.52
CYP19A1 P11511 4/20 0.48
HSD17B10 Q99714 4/20 0.48
CA12 O43570 3/20 0.48
CA4 P22748 3/20 0.48
CA7 P43166 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
AMY1A P0DUB6 2/20 0.48
SLCO2B1 O94956 2/20 0.48
CYP1A1 P04798 2/20 0.48
CYP1A2 P05177 2/20 0.48
PSMB5 P28074 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1B1 Q16678 2/20 0.48
ALOX12 P18054 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3487578 1.00 CYP3A4 (0.52) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL1508796 0.90 MEN1 (0.49) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL16151244 0.89 KDM4E (0.54) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL2781922 0.89 KDM4E (0.54) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL8249167 0.89 KDM4E (0.54) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL28616927 0.88 RECQL (0.44) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL7200862 0.87 CYP1A1 (0.54) CYP3A4MEN1KMT2APTGS1PTGS2
SCHEMBL15544306 0.85 RECQL (0.56) CYP3A4MEN1KMT2APTGS1SYNJ2
SCHEMBL3368235 0.85 CYP19A1 (0.53) CYP3A4PTGS2CYP19A1HSD17B10CA12
SCHEMBL7809366 0.85 CYP19A1 (0.45) CYP3A4MEN1KMT2APTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116519827-A Method for inhibiting sesame pathogenic bacteria active ingredient generated by analyzing penicillium beijerinckii based on non-target metabonomics 河南省农业科学院植物保护研究所 2023-08-01 CN claimed
CN-115710592-B Preparation process of 4',5, 7-trihydroxy flavanone 成都欧康医药股份有限公司 2023-05-26 CN claimed
US-20230119060-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE MEDIENCE CO., LTD. (KR) 2023-04-20 US claimed
CN-115710592-A Preparation process of 4',5, 7-trihydroxy flavanone 成都欧康医药股份有限公司 2023-02-24 CN claimed
CN-104906195-B Reduce the drug and health care product of Urine proteins 中国人民解放军军事医学科学院放射与辐射医学研究所 2019-01-22 CN claimed
EP-2875359-A2 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS Charles R Drew University of Medicine and Science (US) 2015-05-27 EP claimed
WO-2013149258-A2 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS Charles Drew University of Medicine and Science (US) 2013-10-03 WO claimed
EP-1067913-B1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS BIORESPONSE LLC (US) 2012-08-29 EP claimed
WO-2006024545-A1 FUSED BICYCLIC NATURAL COMPOUNDS AND THEIR USE AS INHIBITORS OF PARP AND PARP-MEDIATED INFLAMMATORY PROCESSES STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2006-03-09 WO claimed
US-5770114-A CONSISTS OF AN APROTIC SOLVENT, ELECTROCHROMIC ANODIC AND CATHODIC COMPOUNDS AND ONE BENZOTRIAZOLE DERIVATIVE; RADIATION RESISTANCE GENTEX CORPORATION (US) 1998-06-23 US claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
US-5141745-A Gene expression THE LUBRIZOL CORPORATION (US) 1992-08-25 US claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed
US-20250114380-A1 SMALL MOLECULE CD38 INHIBITORS AND METHODS OF USING SAME PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-04-10 US disclosed
EP-4364744-A1 INHIBITORY AGENT FOR CELL INVASION BY VIRUS Toyo Sugar Refining Co., Ltd. (JP) 2024-05-08 EP disclosed
CN-116519827-A Method for inhibiting sesame pathogenic bacteria active ingredient generated by analyzing penicillium beijerinckii based on non-target metabonomics 河南省农业科学院植物保护研究所 2023-08-01 CN disclosed
EP-0004579-B1 FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1982-08-18 EP disclosed
EP-0051061-A2 Novel intermediates and process for their preparation THE WELLCOME FOUNDATION LIMITED (GB) 1982-05-05 EP disclosed
EP-0004579-A1 Flavans, process for their preparation and pharmaceutical compositions containing them THE WELLCOME FOUNDATION LIMITED (GB) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114380-A1 SMALL MOLECULE CD38 INHIBITORS AND METHODS OF USING SAME CD38, BCL6B, DNASE1L3 CYP3A4 4721/4885MEN1 3469/4885KMT2A 1199/4885
US-20230119060-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE SLC5A2, SLC5A1, SLC5A6 CYP3A4 700/4885MEN1 617/4885KMT2A 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.