SCHEMBL28888693

SCHEMBL28888693

C#CCNC(=O)CCC(C)(C)NC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CNR2 P34972 1/20 0.32
KDM1A O60341 1/20 0.32
MAOB P27338 1/20 0.30
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
NAALAD2 Q9Y3Q0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13407578 0.80 CACNA1H (0.36) ALDH1A1NPC1RAB9ASMN1; SMN2CNR2
SCHEMBL16710792 0.77 CNR2 (0.34) NPC1RAB9ASMN1; SMN2CNR2KDM1A
SCHEMBL21290599 0.74 CNR2 (0.35) NPC1RAB9ASMN1; SMN2CNR2KDM1A
SCHEMBL3494897 0.71 PHF8 (0.46) CNR2KDM1A
SCHEMBL15044593 0.70 CNR2 (0.31) CNR2
SCHEMBL21291278 0.69 CNR2 (0.35) NPC1RAB9ASMN1; SMN2CNR2MAOB
SCHEMBL21071352 0.69 TSHR (0.44) ALDH1A1
SCHEMBL2705007 0.69
SCHEMBL10021727 0.69 FAAH (0.50) SMN1; SMN2CNR2
SCHEMBL13575099 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074835-B Diaryl isoxazoline compound 瑞士伊兰科动物保健有限公司 2020-05-19 CN disclosed