SCHEMBL3494897

SCHEMBL3494897

C#CCNC(=O)CCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 6/20 0.46
KDM2A Q9Y2K7 6/20 0.46
KDM4E B2RXH2 4/20 0.46
KDM5C P41229 4/20 0.46
EGLN1 Q9GZT9 4/20 0.46
KDM6B O15054 2/20 0.46
FOLH1 Q04609 1/20 0.46
KDM7A Q6ZMT4 1/20 0.45
LMNA P02545 2/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
SUCNR1 Q9BXA5 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
BBOX1 O75936 1/20 0.40
HTT P42858 1/20 0.39
SLC15A2 Q16348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2548314 0.87 CYP1A2 (0.47) LMNACYP1A2CYP2D6MAPTCYP2C9
SCHEMBL26315807 0.85 HSD17B10 (0.55) LMNACYP1A2CYP2D6MAPTCYP2C9
SCHEMBL31120963 0.82 ALDH1A1 (0.46) LMNASLC15A2KDM1ACNR2
SCHEMBL29957485 0.81 KDM1A (0.39) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL10021727 0.79 FAAH (0.50) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL2442181 0.79 PHF8 (0.48) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL2705007 0.79
SCHEMBL13575099 0.79
SCHEMBL23987762 0.78 TSHR (0.54) KDM4ELMNAMAPTHSD17B10HTT
SCHEMBL22508727 0.78 TSHR (0.51) CYP1A2CYP2D6MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113249112-B Quantum dot and application thereof 东友精细化工有限公司 2025-02-07 CN disclosed
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
CN-113248953-B Photoconversion curable composition, cured film, quantum dot light-emitting diode, and image display device 东友精细化工有限公司 2023-02-21 CN disclosed
US-11382919-B2 Prevention and treatment of viral infections ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2022-07-12 US disclosed
US-11382919-B2 Prevention and treatment of viral infections ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2022-07-12 US disclosed
US-20210286266-A1 MATERIAL FOR FORMING ORGANIC FILM, METHOD FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-16 US disclosed
CN-113249112-A Quantum dots and applications thereof 东友精细化工有限公司 2021-08-13 CN disclosed
CN-113248953-A Photoconversion curable composition, cured film, quantum dot light-emitting diode, and image display device 东友精细化工有限公司 2021-08-13 CN disclosed
US-20210030887-A1 NON-NATURAL AMATOXIN-TYPE ANTIBODY CONJUGATE SYSTIMMUNE, INC. 2021-02-04 US disclosed
US-20140100154-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors ONYX THERAPEUTICS, INC. (US) 2014-04-10 US disclosed
EP-2696689-A1 USE OF SUBSTITUTED DITHIINE-TETRACARBOXIMIDES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2014-02-19 EP disclosed
US-20140031208-A1 Use of substituted dithiine-tetracarboximides for combating phytopathogenic fungi BASF SE (DE) 2014-01-30 US disclosed
WO-2014011695-A2 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS ONYX THERAPEUTICS, INC. (US) 2014-01-16 WO disclosed
CN-103476259-A Use of substituted dithiine tetracarboximides for combating phytopathogenic fungi BASF SE 2013-12-25 CN disclosed
WO-2012139987-A1 USE OF SUBSTITUTED DITHIINE-TETRACARBOXIMIDES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2012-10-18 WO disclosed
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-06-03 US disclosed
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-06-03 US disclosed
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-06-03 US disclosed
WO-2008110695-A1 NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382919-B2 Prevention and treatment of viral infections SMPD1, PTDSS1, PHOSPHO1 PHF8 1118/4885KDM2A 4366/4885KDM4E 4037/4885
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound EPCAM, CDH1, DNMT3L PHF8 283/4885KDM2A 169/4885KDM4E 104/4885
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS TNFRSF1A, TNFRSF9, CD40 PHF8 4586/4885KDM2A 3933/4885KDM4E 2889/4885
US-20140031208-A1 Use of substituted dithiine-tetracarboximides for combating phytopathogenic fungi TST, TXN, DPM1 PHF8 2828/4885KDM2A 2335/4885KDM4E 2721/4885
US-20140100154-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors PREP, VIP, PEPD PHF8 882/4885KDM2A 684/4885KDM4E 377/4885
US-20210030887-A1 NON-NATURAL AMATOXIN-TYPE ANTIBODY CONJUGATE CD47, ANPEP, NGLY1 PHF8 3806/4885KDM2A 3029/4885KDM4E 4076/4885
US-20210286266-A1 MATERIAL FOR FORMING ORGANIC FILM, METHOD FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND EPCAM, CDH1, DNMT3L PHF8 283/4885KDM2A 169/4885KDM4E 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.