Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 5/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092934 | 0.90 | LCK (0.47) | SMN1; SMN2LCKPI4KBALDH1A1CYP1A2 | |
| SCHEMBL28889072 | 0.88 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2LCKPI4KBALDH1A1 | |
| SCHEMBL28889073 | 0.84 | GCK (0.46) | GCKLCKPI4KB | |
| SCHEMBL28889077 | 0.78 | LCK (0.43) | LCKPI4KBCTSSCTSKCYP2C9 | |
| SCHEMBL28790296 | 0.77 | KDM4E (0.52) | KDM4ESMN1; SMN2PTGDR2ALDH1A1TRPM8 | |
| SCHEMBL27803395 | 0.75 | KDM4E (0.53) | KDM4ESMN1; SMN2PTGDR2ALDH1A1TRPM8 | |
| SCHEMBL27824238 | 0.74 | KDM4E (0.52) | KDM4ESMN1; SMN2PTGDR2CYP1A2TRPM8 | |
| SCHEMBL7424452 | 0.74 | LCK (0.44) | LCKPI4KBALDH1A1CYP1A2CYP2C9 | |
| Bromide SCHEMBL28889082 | 0.73 | KDM4E (0.51) | KDM4ESMN1; SMN2PTGDR2CYP1A2TRPM8 | |
| SCHEMBL29579451 | 0.73 | CA1 (0.40) | GCKLCKPI4KBPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215817-B | 2-aminothiazole-4-acetic acid derivative and preparation method and application thereof | 武汉工程大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-115215817-A | 2-aminothiazole-4-acetic acid derivative and preparation method and application thereof | 武汉工程大学 | 2022-10-21 | — | — | CN | disclosed |