Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 8/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889083 | 0.84 | GCK (0.45) | GCKLCKPI4KB | |
| SCHEMBL28889072 | 0.82 | ALDH1A1 (0.46) | LCKPI4KB | |
| SCHEMBL29092934 | 0.82 | LCK (0.47) | LCKPI4KB | |
| SCHEMBL31311335 | 0.81 | ALDH1A1 (0.48) | LCKABL1 | |
| SCHEMBL31311210 | 0.79 | LCK (0.45) | LCKABL1BRAF | |
| SCHEMBL31311367 | 0.76 | PLTP (0.48) | LCKABL1RORC | |
| SCHEMBL31311187 | 0.76 | LCK (0.48) | LCKABL1 | |
| SCHEMBL29556655 | 0.76 | GCK (0.52) | GCKLCKPI4KB | |
| SCHEMBL29093073 | 0.75 | KDM4E (0.44) | ABL1 | |
| SCHEMBL31311370 | 0.75 | ABL1 (0.71) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215817-B | 2-aminothiazole-4-acetic acid derivative and preparation method and application thereof | 武汉工程大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-115215817-A | 2-aminothiazole-4-acetic acid derivative and preparation method and application thereof | 武汉工程大学 | 2022-10-21 | — | — | CN | disclosed |