Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893638 | 1.00 | MEN1 (0.39) | MEN1KMT2AKDM4EHSP90AA1MAPT | |
| SCHEMBL28889221 | 0.84 | ADRB2 (0.41) | MEN1KMT2AKDM4EHSP90AA1MAPT | |
| SCHEMBL28889298 | 0.81 | ADRB2 (0.39) | MEN1KMT2AL3MBTL1ADRB2KCNH2 | |
| SCHEMBL28959207 | 0.81 | KMT2A (0.40) | MEN1KMT2AKDM4EHSP90AA1MAPT | |
| SCHEMBL28889351 | 0.79 | ADRB2 (0.40) | KDM4EADRB2NOS3NOS2NR3C2 | |
| SCHEMBL24110333 | 0.78 | TACR1 (0.45) | ADRB2NOS3NOS2ALDH1A1 | |
| SCHEMBL28889283 | 0.78 | ADRB2 (0.41) | L3MBTL1ADRB2NOS3NOS2TRPV1 | |
| SCHEMBL29893620 | 0.78 | AURKA (0.40) | ADRB2NOS3NOS2NR3C2 | |
| SCHEMBL28889316 | 0.78 | AURKA (0.40) | ADRB2NOS3NOS2NR3C2 | |
| SCHEMBL28959168 | 0.78 | HDAC4 (0.44) | ADRB2NOS3NOS2NR3C2TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |