Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 11/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889272 | 0.85 | OPRL1 (0.38) | DHODHLNPEP | |
| SCHEMBL29941833 | 0.81 | HDAC4 (0.41) | HDAC4DHODHHDAC3HDAC7HDAC8 | |
| SCHEMBL30637660 | 0.80 | HDAC4 (0.41) | HDAC4GAAHDAC3HDAC7HDAC8 | |
| SCHEMBL28889296 | 0.80 | HDAC4 (0.40) | HDAC4DHODHHDAC3HDAC7HDAC8 | |
| SCHEMBL28889263 | 0.79 | HDAC4 (0.41) | HDAC4GAAHDAC3HDAC7HDAC8 | |
| SCHEMBL28889192 | 0.78 | HDAC4 (0.39) | HDAC4DHODHHDAC3HDAC7HDAC8 | |
| SCHEMBL28959168 | 0.78 | HDAC4 (0.44) | HDAC4GAAHDAC3HDAC7HDAC8 | |
| SCHEMBL29942045 | 0.77 | HDAC4 (0.46) | HDAC4GAAHDAC3HDAC7HDAC8 | |
| SCHEMBL28889317 | 0.76 | ALDH1A1 (0.40) | HDAC4DHODHGAA | |
| SCHEMBL17316873 | 0.70 | HDAC4 (0.49) | HDAC4GAAHDAC3HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222911-A1 | PYRIMIDONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |