Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 16/20 | 0.63 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723573 | 0.83 | NPBWR1 (0.65) | NPBWR1MCHR1ALDH1A1KDM4EMAPT | |
| SCHEMBL27741430 | 0.81 | NPBWR1 (0.63) | NPBWR1MCHR1ALDH1A1KDM4EMAPT | |
| SCHEMBL14844531 | 0.80 | NPBWR1 (0.84) | NPBWR1MCHR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2551062 | 0.79 | NPBWR1 (0.77) | NPBWR1MCHR1ALDH1A1MAPTHTT | |
| SCHEMBL24687649 | 0.78 | NPBWR1 (0.75) | NPBWR1MCHR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL25045656 | 0.76 | NPBWR1 (0.57) | NPBWR1MCHR1ALDH1A1KDM4EMAPT | |
| SCHEMBL13723877 | 0.76 | NPBWR1 (0.60) | NPBWR1MCHR1MAPTSMN1; SMN2 | |
| SCHEMBL13724241 | 0.76 | NPBWR1 (0.56) | NPBWR1MCHR1ALDH1A1KDM4EMAPT | |
| SCHEMBL20138946 | 0.75 | NPBWR1 (0.56) | NPBWR1MCHR1ALDH1A1KDM4EMAPT | |
| SCHEMBL16014396 | 0.75 | NPBWR1 (0.52) | NPBWR1MCHR1ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652289-B | Substituted tricyclic compounds as FGFR inhibitors | 因塞特控股公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-107383009-B | Substituted tricyclic compounds as FGFR inhibitors | 因塞特控股公司 | 2020-06-09 | — | — | CN | disclosed |