Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.41 |
| ▸ | CA1 | P00915 | 12/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258334 | 0.85 | CA2 (0.50) | CA2CA1CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL8000907 | 0.83 | MAPT (0.50) | CA2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27647793 | 0.83 | CA1 (0.48) | CA2CA1CA4 | |
| SCHEMBL11039771 | 0.83 | KMT2A (0.50) | CA2CA1CA9ALDH1A1MAPT | |
| SCHEMBL2169178 | 0.81 | ALDH1A1 (0.50) | CA2ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL1246773 | 0.80 | CA2 (0.48) | CA2CA1CA9ALDH1A1TSHR | |
| SCHEMBL1244831 | 0.79 | CA2 (0.35) | CA2ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL3142520 | 0.79 | KMT2A (0.51) | CA2CA1CA9ALDH1A1NPC1 | |
| Alcohol SCHEMBL11039769 | 0.79 | KMT2A (0.46) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27851342 | 0.79 | HPGD (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115380026-B | Protein degradation modulators and methods of use thereof | 南京明德新药研发有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115380026-A | Protein degradation modulators and methods of use thereof | 南京明德新药研发有限公司 | 2022-11-22 | — | — | CN | disclosed |